Ligand Activation of the Androgen Receptor Downregulates E-Cadherin-Mediated Cell Adhesion and Promotes Apoptosis of Prostatic Cancer Cells

Androgen independence is the major cause of endocrine therapy failure in advanced prostate cancer (PC). To examine the effects of human androgen receptor (AR) expression on growth of human PC cells, transfection of full-length AR cDNA in an androgen-insensitive human prostatic adenocarcinoma cell li...

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Main Authors: Nightingale, Joanna, Chaudhary, Khurram S, Abel, Paul D, Stubbs, Andrew P, Romanska, Hanna M, Mitchell, Stephen E, Stamp, Gordon W H, Lalani, El-Nasir
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2003
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502422/
https://ncbi.nlm.nih.gov/pubmed/14511406
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