Structural effect of the anticancer agent 6-thioguanine on duplex DNA
The incorporation of 6-thioguanine (S6G) into DNA is an essential step in the cytotoxic activity of thiopurines. However, the structural effects of this substitution on duplex DNA have not been fully characterized. Here, we present the solution structures of DNA duplexes containing S6G opposite thym...
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| Publicado en: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12582253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg203 |
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