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Ribavirin in Cancer Immunotherapies: Controlling Nitric Oxide Augments Cytotoxic Lymphocyte Function

Either ribavirin (RBV) or cyclophosphamide (CY) can shift an immune response from Th2 toward a Th1 cytokine profile. CY is used in this role in various current cancer immunotherapy attempts but with mixed success. More potent and reliable immunoadjuvants and Th1 response biasing methods are needed....

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Bibliographic Details
Main Author: Kast, Richard E
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502126/
https://ncbi.nlm.nih.gov/pubmed/12659664
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