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WISP3 (CCN6) Is a Secreted Tumor-Suppressor Protein that Modulates IGF Signaling in Inflammatory Breast Cancer

Inflammatory breast cancer (IBC) is the most lethal form of locally advanced breast cancer. We have found that WISP3 is lost in 80% of human IBC tumors and that it has growth- and angiogenesis-inhibitory functions in breast cancer in vitro and in vivo. WISP3 is a cysteine-rich, putatively secreted p...

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Bibliografske podrobnosti
Main Authors: Kleer, Celina G, Zhang, Yanhong, Pan, Quintin, Merajver, Sofia D
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502087/
https://ncbi.nlm.nih.gov/pubmed/15140407
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