Persistent STAT3 Activation in Colon Cancer Is Associated with Enhanced Cell Proliferation and Tumor Growth

Colorectal carcinoma (CRC) is a major cause of morbidity and mortality in Western countries. It has so far been molecularly defined mainly by alterations of the Wnt pathway. We show here for the first time that aberrant activities of the signal transducer and activator of transcription STAT3 activel...

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Detalhes bibliográficos
Main Authors: Corvinus, Florian M, Orth, Carina, Moriggl, Richard, Tsareva, Svetlana A, Wagner, Stefan, Pfitzner, Edith B, Baus, Daniela, Kaufmann, Roland, Huberb, Lukas A, Zatloukal, Kurt, Beug, Hartmut, Öhlschläger, Peter, Schütz, Alexander, Halbhuber, Karl-Jürgen, Friedrich, Karlheinz
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501283/
https://ncbi.nlm.nih.gov/pubmed/16036105
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