The Minimal Set of Genetic Alterations Required for Conversion of Primary Human Fibroblasts to Cancer Cells in the Subrenal Capsule Assay

Based on previous studies, a minimal set of genetic alterations that is required to convert normal human fibroblasts into cancer cells has been defined. Essential roles for telomere maintenance and alterations in phosphatase 2A activity were inferred from experiments in which tumorigenicity was test...

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Bibliografiske detaljer
Main Authors: Sun, Beicheng, Chen, Meizhen, Hawks, Christina L, Pereira-Smith, Olivia M, Hornsby, Peter J
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501282/
https://ncbi.nlm.nih.gov/pubmed/16036109
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