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Efficacy of Deguelin and Silibinin on Benzo(a)pyrene-Induced Lung Tumorigenesis in A/J Mice

We evaluated deguelin and silibinin in A/J mice treated with the tobacco-specific carcinogen benzo(a)pyrene (BP) for their ability to inhibit pulmonary adenoma formation and growth. Animals were treated with either deguelin (5.0 or 10.0 mg/kg body weight, by gavage) or silibinin at doses of 0.05% an...

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Detalhes bibliográficos
Main Authors: Yan, Ying, Wang, Yian, Tan, Qing, Lubet, Ronald A, You, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501176/
https://ncbi.nlm.nih.gov/pubmed/16354587
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