The Characteristics of Astrocytomas and Oligodendrogliomas Are Caused by Two Distinct and Interchangeable Signaling Formats

Chronic platelet-derived growth factor (PDGF) signaling in glial progenitors leads to the formation of oligodendrogliomas in mice, whereas chronic combined Ras and Akt signaling leads to astrocytomas. Different histologies of these tumors imply that the pathways activated by these two oncogenic stim...

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Bibliografiske detaljer
Main Authors: Dai, Chengkai, Lyustikman, Yelena, Shih, Alan, Hu, Xiaoyi, Fuller, Gregory N, Rosenblum, Marc, Holland, Eric C
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501153/
https://ncbi.nlm.nih.gov/pubmed/15967117
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