X-ray crystal structure of MENT: evidence for functional loop–sheet polymers in chromatin condensation

Most serpins are associated with protease inhibition, and their ability to form loop–sheet polymers is linked to conformational disease and the human serpinopathies. Here we describe the structural and functional dissection of how a unique serpin, the non-histone architectural protein, MENT (Myeloid...

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Detaylı Bibliyografya
Asıl Yazarlar: McGowan, Sheena, Buckle, Ashley M, Irving, James A, Ong, Poh Chee, Bashtannyk-Puhalovich, Tanya A, Kan, Wan-Ting, Henderson, Kate N, Bulynko, Yaroslava A, Popova, Evgenya Y, Smith, A Ian, Bottomley, Stephen P, Rossjohn, Jamie, Grigoryev, Sergei A, Pike, Robert N, Whisstock, James C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500978/
https://ncbi.nlm.nih.gov/pubmed/16810322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601201
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