X-ray crystal structure of MENT: evidence for functional loop–sheet polymers in chromatin condensation

Most serpins are associated with protease inhibition, and their ability to form loop–sheet polymers is linked to conformational disease and the human serpinopathies. Here we describe the structural and functional dissection of how a unique serpin, the non-histone architectural protein, MENT (Myeloid...

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Main Authors: McGowan, Sheena, Buckle, Ashley M, Irving, James A, Ong, Poh Chee, Bashtannyk-Puhalovich, Tanya A, Kan, Wan-Ting, Henderson, Kate N, Bulynko, Yaroslava A, Popova, Evgenya Y, Smith, A Ian, Bottomley, Stephen P, Rossjohn, Jamie, Grigoryev, Sergei A, Pike, Robert N, Whisstock, James C
פורמט: Artigo
שפה:Inglês
יצא לאור: 2006
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500978/
https://ncbi.nlm.nih.gov/pubmed/16810322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601201
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