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Detecting non-orthology in the COGs database and other approaches grouping orthologs using genome-specific best hits

Correct orthology assignment is a critical prerequisite of numerous comparative genomics procedures, such as function prediction, construction of phylogenetic species trees and genome rearrangement analysis. We present an algorithm for the detection of non-orthologs that arise by mistake in current...

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Detalhes bibliográficos
Main Authors: Dessimoz, Christophe, Boeckmann, Brigitte, Roth, Alexander C. J., Gonnet, Gaston H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500873/
https://ncbi.nlm.nih.gov/pubmed/16835308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl433
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