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Sema4D/plexin-B1 activates GSK-3β through R-Ras GAP activity, inducing growth cone collapse

Plexins are receptors for the axonal guidance molecules known as semaphorins, and the semaphorin 4D (Sema4D) receptor plexin-B1 induces repulsive responses by functioning as an R-Ras GTPase-activating protein (GAP). Here we characterized the downstream signalling of plexin-B1-mediated R-Ras GAP acti...

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Detalhes bibliográficos
Main Authors: Ito, Yuri, Oinuma, Izumi, Katoh, Hironori, Kaibuchi, Kozo, Negishi, Manabu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500830/
https://ncbi.nlm.nih.gov/pubmed/16799460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400737
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