Constitutive Macropinocytosis in Oncogene-transformed Fibroblasts Depends on Sequential Permanent Activation of Phosphoinositide 3-Kinase and Phospholipase C

Macropinocytosis results from the closure of lamellipodia generated by membrane ruffling, thereby reflecting cortical actin dynamics. Both transformation of Rat-1 fibroblasts by v-Src or K-Ras and stable transfection for expression of dominant-positive, wild-type phosphoinositide 3-kinase (PI3K) reg...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Amyere, Mustapha, Payrastre, Bernard, Krause, Ulrike, Smissen, Patrick Van Der, Veithen, Alex, Courtoy, Pierre J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11029048/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.10.3453
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