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RACK1 Regulates Integrin-mediated Adhesion, Protrusion, and Chemotactic Cell Migration via Its Src-binding Site

Mammalian cDNA expression cloning was used to identify novel regulators of integrin-mediated cell-substratum adhesions. Using a focal adhesion morphology screen, we identified a cDNA with homology to a receptor for activated protein kinase C (RACK1) that induced a loss of central focal adhesions and...

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Detalhes bibliográficos
Main Authors: Cox, Elisabeth A., Bennin, David, Doan, Ashley T., O'Toole, Timothy, Huttenlocher, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149999/
https://ncbi.nlm.nih.gov/pubmed/12589061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-03-0142
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