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Matricellular Proteins as Modulators of Cell–Matrix Interactions: Adhesive Defect in Thrombospondin 2-null Fibroblasts is a Consequence of Increased Levels of Matrix Metalloproteinase-2

Thrombospondin 2 (TSP2)-null mice, generated by disruption of the Thbs2 gene, display a variety of connective tissue abnormalities, including fragile skin and the presence of abnormally large collagen fibrils with irregular contours in skin and tendon. In this study we demonstrate that TSP2-null ski...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Yang, Zhantao, Kyriakides, Themis R., Bornstein, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14997/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11029041/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.10.3353
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