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Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia

To better understand the function of the conserved C terminus of the cystic fibrosis (CF) transmembrane conductance regulator, we studied constructs containing deletions in the C-terminal tail. When expressed in well differentiated CF airway epithelia, each construct localized predominantly to the a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ostedgaard, Lynda S., Randak, Christoph, Rokhlina, Tatiana, Karp, Philip, Vermeer, Daniel, Ashbourne Excoffon, Katherine J., Welsh, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12578973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2627982100
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