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Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB

α-N-Acetylglucosaminidase deficiency (mucopolysaccharidosis IIIB, MPS IIIB) and α-l-iduronidase deficiency (MPS I) are heritable lysosomal storage diseases; neurodegeneration is prominent in MPS IIIB and in severe cases of MPS I. We have obtained morphologic and molecular evidence for the involvemen...

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Detalhes bibliográficos
Main Authors: Ohmi, Kazuhiro, Greenberg, David S., Rajavel, Kavitha S., Ryazantsev, Sergey, Li, Hong Hua, Neufeld, Elizabeth F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149931/
https://ncbi.nlm.nih.gov/pubmed/12576554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252784899
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