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Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain

FGF8 is known to be an important regulator of forebrain development. Here, we investigated the effects of varying the level of Fgf8 expression in the mouse forebrain. We detected two distinct responses, one that was proportionate with Fgf8 expression and another that was not. The latter response, wh...

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Detalhes bibliográficos
Main Authors: Storm, Elaine E., Rubenstein, John L. R., Martin, Gail R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149906/
https://ncbi.nlm.nih.gov/pubmed/12574514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337736100
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