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Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice
The Scar/WAVE family of scaffolding proteins organize molecular networks that relay signals from the GTPase Rac to the actin cytoskeleton. The WAVE-1 isoform is a brain-specific protein expressed in variety of areas including the regions of the hippocampus and the Purkinje cells of the cerebellum. T...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149900/ https://ncbi.nlm.nih.gov/pubmed/12578964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0438033100 |
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