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Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice

The Scar/WAVE family of scaffolding proteins organize molecular networks that relay signals from the GTPase Rac to the actin cytoskeleton. The WAVE-1 isoform is a brain-specific protein expressed in variety of areas including the regions of the hippocampus and the Purkinje cells of the cerebellum. T...

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Detalhes bibliográficos
Main Authors: Soderling, Scott H., Langeberg, Lorene K., Soderling, Jacquelyn A., Davee, Stephen M., Simerly, Richard, Raber, Jacob, Scott, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149900/
https://ncbi.nlm.nih.gov/pubmed/12578964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0438033100
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