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Associative memory Hamiltonians for structure prediction without homology: α/β proteins

We describe a method for predicting the structure of α/β class proteins in the absence of information from homologous structures. The method is based on an associative memory model for short to intermediate range in sequence contacts and a contact potential for long range in sequence contacts. The c...

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Bibliografiske detaljer
Main Authors: Hardin, Corey, Eastwood, Michael P., Prentiss, Michael C., Luthey-Schulten, Zadia, Wolynes, Peter G.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149892/
https://ncbi.nlm.nih.gov/pubmed/12554830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252753899
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