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Coordinate inhibition of expression of several genes for protein subunits of human nuclear RNase P

The deliberate inhibition of expression of one of the protein subunits (Rpp38) of human nuclear RNase P is achievable by using external guide sequence (EGS) technology. Both the protein product and the mRNA are greatly reduced 24 h after transient transfection with a gene coding for an appropriate E...

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Detalhes bibliográficos
Main Authors: Kovrigina, Elizaveta, Wesolowski, Donna, Altman, Sidney
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149878/
https://ncbi.nlm.nih.gov/pubmed/12552092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337661100
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