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Assembly of core helices and rapid tertiary folding of a small bacterial group I ribozyme

Compact but non-native intermediates have been implicated in the hierarchical folding of several large RNAs, but there is little information on their structure. In this article, ribonuclease and hydroxyl radical cleavage protection assays showed that base pairing of core helices stabilize a compact...

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Main Authors: Rangan, Prashanth, Masquida, Benoît, Westhof, Eric, Woodson, Sarah A.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC149874/
https://ncbi.nlm.nih.gov/pubmed/12574513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337743100
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