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The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity

The gene EPXH2 encodes for the soluble epoxide hydrolase (sEH), an enzyme involved in the regulation of cardiovascular and renal physiology containing two distinct domains connected via a proline-rich linker. The C-terminal domain containing the EH catalytic activity has been well studied. In contra...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Newman, John W., Morisseau, Christophe, Harris, Todd R., Hammock, Bruce D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149871/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0437724100
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