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Duplication of U3 Sequences in the Long Terminal Repeat of Mink Cell Focus-Inducing Viruses Generates Redundancies of Transcription Factor Binding Sites Important for the Induction of Thymomas

The ability of mink cell focus-inducing (MCF) viruses to induce thymomas is determined, in part, by transcriptional enhancers in the U3 region of their long terminal repeats (LTRs). To elucidate sequence motifs important for enhancer function in vivo, we injected newborn mice with MCF 1dr (supF), a...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: DiFronzo, Nancy L., Frieder, Marisa, Loiler, Scott A., Pham, Quynh N., Holland, Christie A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149780/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12584358/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.5.3326-3333.2003
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