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Reconstitution of Brefeldin A–induced Golgi Tubulation and Fusion with the Endoplasmic Reticulum in Semi-Intact Chinese Hamster Ovary Cells

The fungal metabolite brefeldin A (BFA) induces the disassembly of the Golgi complex in mammalian cells. The drug seems to accentuate tubule formation and causes the subsequent fusion with the endoplasmic reticulum (ER). To investigate the biochemical requirements and kinetics of BFA-induced Golgi d...

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Bibliographic Details
Main Authors: Kano, Fumi, Sako, Yasushi, Tagaya, Mitsuo, Yanagida, Toshio, Murata, Masayuki
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC14976/
https://ncbi.nlm.nih.gov/pubmed/10982401
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