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Human Parvovirus B19 Nonstructural Protein (NS1) Induces Cell Cycle Arrest at G(1) Phase

Human parvovirus B19 infects predominantly erythroid precursor cells, leading to inhibition of erythropoiesis. This erythroid cell damage is mediated by the viral nonstructural protein 1 (NS1) through an apoptotic mechanism. We previously demonstrated that B19 virus infection induces G(2) arrest in...

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Main Authors: Morita, Eiji, Nakashima, Akitoshi, Asao, Hironobu, Sato, Hiroyuki, Sugamura, Kazuo
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC149759/
https://ncbi.nlm.nih.gov/pubmed/12584315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.2915-2921.2003
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