Cell Contact–dependent Activation of α3β1 Integrin Modulates Endothelial Cell Responses to Thrombospondin-1

Thrombospondin-1 (TSP1) can inhibit angiogenesis by interacting with endothelial cell CD36 or proteoglycan receptors. We have now identified α3β1 integrin as an additional receptor for TSP1 that modulates angiogenesis and the in vitro behavior of endothelial cells. Recognition of TSP1 and an α3β1 in...

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Publicat a:	Mol Biol Cell
Autors principals:	Chandrasekaran, Lakshmi, He, Chao-Zhen, Al-Barazi, Hebah, Krutzsch, Henry C., Iruela-Arispe, M. Luisa, Roberts, David D.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Cell Biology 2000
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14963/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982388/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.9.2885
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