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The Internal Phosphodiesterase RegA Is Essential for the Suppression of Lateral Pseudopods during Dictyostelium Chemotaxis

Dictyostelium strains in which the gene encoding the cytoplasmic cAMP phosphodiesterase RegA is inactivated form small aggregates. This defect was corrected by introducing copies of the wild-type regA gene, indicating that the defect was solely the consequence of the loss of the phosphodiesterase. U...

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Detalhes bibliográficos
Main Authors: Wessels, Deborah J., Zhang, Hui, Reynolds, Joshua, Daniels, Karla, Heid, Paul, Lu, Sijie, Kuspa, Adam, Shaulsky, Gad, Loomis, William F., Soll, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14957/
https://ncbi.nlm.nih.gov/pubmed/10930471
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