Genetic Fate of Recombinant Adeno-Associated Virus Vector Genomes in Muscle

Recombinant adeno-associated virus (rAAV) vectors are promising human gene transfer vectors, because they mediate long-term gene expression in vivo. The vector DNA form responsible for sustained gene expression has not been clearly defined, but it has been presumed that the vector integrates to some...

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Библиографические подробности
Главные авторы: Schnepp, Bruce C., Clark, K. Reed, Klemanski, Dori L., Pacak, Christina A., Johnson, Philip R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
Предметы:
Gene Therapy
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC149530/
https://ncbi.nlm.nih.gov/pubmed/12610125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3495-3504.2003
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