Transmembrane Domains 1 and 2 of the Latent Membrane Protein 1 of Epstein-Barr Virus Contain a Lipid Raft Targeting Signal and Play a Critical Role in Cytostasis

The latent membrane protein 1 (LMP-1) oncoprotein of Epstein-Barr virus (EBV) is a constitutively active, CD40-like cell surface signaling protein essential for EBV-mediated human B-cell immortalization. Like ligand-activated CD40, LMP-1 activates NF-κB and Jun kinase signaling pathways via binding,...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Coffin III, William F., Geiger, Timothy R., Martin, Jennifer M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Transformation and Oncogenesis
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149527/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12610149/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.6.3749-3758.2003
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