An Amino Acid in the Central Catalytic Domain of Three Retroviral Integrases That Affects Target Site Selection in Nonviral DNA

Integrase can insert retroviral DNA into almost any site in cellular DNA; however, target site preferences are noted in vitro and in vivo. We recently demonstrated that amino acid 119, in the α2 helix of the central domain of the human immunodeficiency virus type 1 integrase, affected the choice of...

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Pubblicato in:	J Virol
Autori principali:	Harper, Amy L., Sudol, Malgorzata, Katzman, Michael
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12610159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.6.3838-3845.2003
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