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Specific Sequence Motif of 8-Cys Repeats of TGF-β Binding Proteins, LTBPs, Creates a Hydrophobic Interaction Surface for Binding of Small Latent TGF-β

Transforming growth factor (TGF)-βs are secreted in large latent complexes consisting of TGF-β, its N-terminal latency-associated peptide (LAP) propeptide, and latent TGF-β binding protein (LTBP). LTBPs are required for secretion and subsequent deposition of TGF-β into the extracellular matrix. TGF-...

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Detalhes bibliográficos
Main Authors: Saharinen, Juha, Keski-Oja, Jorma
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14949/
https://ncbi.nlm.nih.gov/pubmed/10930463
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