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Human Cytomegalovirus pp71 Stimulates Cell Cycle Progression by Inducing the Proteasome-Dependent Degradation of the Retinoblastoma Family of Tumor Suppressors

The oncoproteins of the DNA tumor viruses, adenovirus E1A, simian virus 40 T antigen, and papillomavirus E7, each interact with the retinoblastoma family of tumor suppressors, leading to cell cycle stimulation, apoptosis induction, and cellular transformation. These proteins utilize a conserved LXCX...

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書誌詳細
主要な著者: Kalejta, Robert F., Bechtel, Jill T., Shenk, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC149485/
https://ncbi.nlm.nih.gov/pubmed/12612064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.6.1885-1895.2003
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