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Evidence for DNA Translocation by the ISWI Chromatin-Remodeling Enzyme

The ISWI proteins form the catalytic core of a subset of ATP-dependent chromatin-remodeling activities. Here, we studied the interaction of the ISWI protein with nucleosomal substrates. We found that the ability of nucleic acids to bind and stimulate the ATPase activity of ISWI depends on length. We...

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Autori principali: Whitehouse, Iestyn, Stockdale, Chris, Flaus, Andrew, Szczelkun, Mark D., Owen-Hughes, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC149479/
https://ncbi.nlm.nih.gov/pubmed/12612068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.6.1935-1945.2003
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