Lack of involvement of known DNA methyltransferases in familial hydatidiform mole implies the involvement of other factors in establishment of imprinting in the human female germline

BACKGROUND: Differential methylation of the two alleles is a hallmark of imprinted genes. Correspondingly, loss of DNA methyltransferase function results in aberrant imprinting and abnormal post-fertilization development. In the mouse, mutations of the oocyte-specific isoform of the DNA methyltransf...

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Detalhes bibliográficos
Main Authors: Hayward, B E, De Vos, M, Judson, H, Hodge, D, Huntriss, J, Picton, H M, Sheridan, E, Bonthron, DT
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149328/
https://ncbi.nlm.nih.gov/pubmed/12546714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-2
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