ABT-773: Pharmacokinetics and Interactions with Ranitidine and Sucralfate

We assessed the pharmacokinetics and interaction of ABT-773 in 12 volunteers receiving ABT-773 alone or concomitantly with ranitidine or sucralfate. Data for 150 mg of ABT-773 were as follows: the maximum concentration of the drug in plasma (C(max)) was 318 ng/ml, its half-life was 5.66 h, and its a...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Pletz, M. W., Preechachatchaval, V., Bulitta, J., Allewelt, M., Burkhardt, O., Lode, H.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Pharmacology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149283/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12604553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.3.1129-1131.2003
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