VAMP2, but Not VAMP3/Cellubrevin, Mediates Insulin-dependent Incorporation of GLUT4 into the Plasma Membrane of L6 Myoblasts

Like neuronal synaptic vesicles, intracellular GLUT4-containing vesicles must dock and fuse with the plasma membrane, thereby facilitating insulin-regulated glucose uptake into muscle and fat cells. GLUT4 colocalizes in part with the vesicle SNAREs VAMP2 and VAMP3. In this study, we used a single-ce...

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Auteurs principaux: Randhawa, Varinder K., Bilan, Philip J., Khayat, Zayna A., Daneman, Nicholas, Liu, Zhi, Ramlal, Toolsie, Volchuk, Allen, Peng, Xiao-Rong, Coppola, Thierry, Regazzi, Romano, Trimble, William S., Klip, Amira
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC14928/
https://ncbi.nlm.nih.gov/pubmed/10888677
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