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Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression

Activation of transcription factors by receptor mediated signaling is an essential step for T lymphocyte effector function. Following antigenic stimulation of T cells the two central cytokines IL-2 and TNFα are co-expressed and co-regulated. Two important transcription factors, i.e., early growth re...

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Autors principals: Decker, Eva L., Nehmann, Nina, Kampen, Eva, Eibel, Hermann, Zipfel, Peter F., Skerka, Christine
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149206/
https://ncbi.nlm.nih.gov/pubmed/12560487
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