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Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression
Activation of transcription factors by receptor mediated signaling is an essential step for T lymphocyte effector function. Following antigenic stimulation of T cells the two central cytokines IL-2 and TNFα are co-expressed and co-regulated. Two important transcription factors, i.e., early growth re...
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Autors principals: | , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Oxford University Press
2003
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149206/ https://ncbi.nlm.nih.gov/pubmed/12560487 |
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