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Insights into the Structural Organization of the I1 Inner Arm Dynein from a Domain Analysis of the 1β Dynein Heavy Chain

To identify domains in the dynein heavy chain (Dhc) required for the assembly of an inner arm dynein, we characterized a new motility mutant (ida2-6) obtained by insertional mutagenesis. ida2-6 axonemes lack the polypeptides associated with the I1 inner arm complex. Recovery of genomic DNA flanking...

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Main Authors: Perrone, Catherine A., Myster, Steven H., Bower, Raqual, O'Toole, Eileen T., Porter, Mary E.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC14920/
https://ncbi.nlm.nih.gov/pubmed/10888669
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