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Mismatch repair activity in mammalian mitochondria

Mitochondrial DNA (mtDNA) defects cause debilitating metabolic disorders for which there is no effective treatment. Patients suffering from these diseases often harbour both a wild-type and a mutated subpopulation of mtDNA, a situation termed heteroplasmy. Understanding mtDNA repair mechanisms could...

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Bibliografiske detaljer
Main Authors: Mason, Penelope A., Matheson, Elizabeth C., Hall, Andrew G., Lightowlers, Robert N.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149189/
https://ncbi.nlm.nih.gov/pubmed/12560503
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