Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion
In vitro homotypic fusion of yeast vacuoles occurs in three stages: priming, the Sec18 (NSF)-mediated changes that precede vacuole association; docking, the Ypt7 and SNARE-mediated pairing of vacuoles; and fusion, mediated by calmodulin/V0/t-SNARE interactions. Defects in catalysts of each stage res...
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| Published in: | EMBO J |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.15.4035 |
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