Loading...

Murine Guanylate-binding Protein: Incomplete Geranylgeranyl Isoprenoid Modification of an Interferon-γ–inducible Guanosine Triphosphate-binding Protein

Farnesylation of Ras proteins is necessary for transforming activity. Although farnesyl transferase inhibitors show promise as anticancer agents, prenylation of the most commonly mutated Ras isoform, K-Ras4B, is difficult to prevent because K-Ras4B can be alternatively modified with geranylgeranyl (...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Stickney, John T., Buss, Janice E.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14912/
https://ncbi.nlm.nih.gov/pubmed/10888661
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!