CpG DNA modulates interleukin 1β-induced interleukin-8 expression in human bronchial epithelial (16HBE14o-) cells

BACKGROUND: Recognition of repeat unmethylated CpG motifs from bacterial DNA through Toll-like receptor (TLR-9) has been shown to induce interleukin (IL)-8 expression in immune cells. We sought to investigate the role of CpG oligodeoxynucleotides (ODN) on a human bronchial epithelial cells. METHODS:...

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Detalhes bibliográficos
Main Authors: Parilla, N William, Hughes, Valerie S, Lierl, Kristin M, Wong, Hector R, Page, Kristen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489942/
https://ncbi.nlm.nih.gov/pubmed/16740161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-84
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