Pharmacokinetics of Telbivudine in Healthy Subjects and Absence of Drug Interaction with Lamivudine or Adefovir Dipivoxil

Two phase I studies were conducted to assess the plasma pharmacokinetics of telbivudine and potential drug-drug interactions between telbivudine (200 or 600 mg/day) and lamivudine (100 mg/day) or adefovir dipivoxil (10 mg/day) in healthy subjects. Study drugs were administered orally. The pharmacoki...

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Bibliographic Details
Main Authors: Zhou, Xiao-Jian, Fielman, Barbara A., Lloyd, Deborah M., Chao, George C., Brown, Nathaniel A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489765/
https://ncbi.nlm.nih.gov/pubmed/16801406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01313-05
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