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Intracellular Transport, Assembly, and Degradation of Wild-Type and Disease-linked Mutant Gap Junction Proteins

More than 130 different mutations in the gap junction integral plasma membrane protein connexin32 (Cx32) have been linked to the human peripheral neuropathy X-linked Charcot–Marie–Tooth disease (CMTX). How these various mutants are processed by the cell and the mechanism(s) by which they cause CMTX...

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Bibliografiske detaljer
Main Authors: VanSlyke, Judy K., Deschenes, Suzanne M., Musil, Linda S.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14894/
https://ncbi.nlm.nih.gov/pubmed/10848620
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