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A Novel Selection Regime for Differentiation Defects Demonstrates an Essential Role for the Stumpy Form in the Life Cycle of the African Trypanosome

A novel selection scheme has been developed to isolate bloodstream forms of Trypanosoma brucei, which are defective in their ability to differentiate to the procyclic stage. Detailed characterization of one selected cell line (defective in differentiation clone 1 [DiD-1]) has demonstrated that these...

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Pubblicato in:Mol Biol Cell
Autori principali: Tasker, Maria, Wilson, Judith, Sarkar, Mitali, Hendriks, Ed, Matthews, Keith
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14892/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10793160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.5.1905
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