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Structure–Function Relationships in Yeast Tubulins

A comprehensive set of clustered charged-to-alanine mutations was generated that systematically alter TUB1, the major α-tubulin gene of Saccharomyces cerevisiae. A variety of phenotypes were observed, including supersensitivity and resistance to the microtubule-destabilizing drug benomyl, lethality,...

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Auteurs principaux: Richards, Kristy L., Anders, Kirk R., Nogales, Eva, Schwartz, Katja, Downing, Kenneth H., Botstein, David
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC14891/
https://ncbi.nlm.nih.gov/pubmed/10793159
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