Humoral Responses against Coimmunized Protein Antigen but Not against Alphavirus-Encoded Antigens Require Alpha/Beta Interferon Signaling

Viruses typically elicit potent adaptive immune responses, and live-virus-based vaccines are among the most efficient human vaccines known. The mechanisms by which viruses stimulate adaptive immune responses are not fully understood, but activation of innate immune signaling pathways in the early ph...

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Bibliographic Details
Main Authors: Hidmark, Åsa S., Nordström, Eva K. L., Dosenovic, Pia, Forsell, Mattias N. E., Liljeström, Peter, Karlsson Hedestam, Gunilla B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489049/
https://ncbi.nlm.nih.gov/pubmed/16809315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02579-05
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