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Involvement of a Small GTP-binding Protein (G Protein) Regulator, Small G Protein GDP Dissociation Stimulator, in Antiapoptotic Cell Survival Signaling

Small GTP-binding protein GDP dissociation stimulator (Smg GDS) regulates GDP/GTP exchange reaction of Ki-Ras and the Rho and Rap1 family members and inhibits their binding to membranes. In fibroblasts, Smg GDS shows mitogenic and transforming activities in cooperation with Ki-Ras. However, the phys...

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Detalhes bibliográficos
Main Authors: Takakura, Ayumi, Miyoshi, Jun, Ishizaki, Hiroyoshi, Tanaka, Miki, Togawa, Atsushi, Nishizawa, Yasuko, Yoshida, Hisahiro, Nishikawa, Shin-ichi, Takai, Yoshimi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14890/
https://ncbi.nlm.nih.gov/pubmed/10793158
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