A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis

BACKGROUND: The cause of neuronal death in amyotrophic lateral sclerosis (ALS) is uncertain but mitochondrial dysfunction may play an important role. Ketones promote mitochondrial energy production and membrane stabilization. RESULTS: SOD1-G93A transgenic ALS mice were fed a ketogenic diet (KD) base...

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Autori principali: Zhao, Zhong, Lange, Dale J, Voustianiouk, Andrei, MacGrogan, Donal, Ho, Lap, Suh, Jason, Humala, Nelson, Thiyagarajan, Meenakshisundaram, Wang, Jun, Pasinetti, Giulio M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1488864/
https://ncbi.nlm.nih.gov/pubmed/16584562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-7-29
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