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Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics

BACKGROUND: Gene transcriptional activity is well correlated with intra-nuclear position, especially relative to the nuclear periphery, which is a region classically associated with gene silencing. Recently however, actively transcribed genes have also been found localized to the nuclear periphery i...

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Detalhes bibliográficos
Main Authors: Drubin, David A, Garakani, Arman M, Silver, Pamela A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1488840/
https://ncbi.nlm.nih.gov/pubmed/16635267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-7-19
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